Product name: |
Caspase 9 Mouse mAb |
Reactivity: |
Human, Rat, Mouse |
Alternative Names: |
APAF 3 antibody, Apoptosis related cysteine peptidase antibody, Apoptotic protease-activating factor 3 antibody, CASP 9 antibody |
Source: |
Mouse |
Dilutions: |
WB 1:1,000-5,000 IP 1:200 IF 1:100-200 |
Immunogen: |
Synthetic Peptide |
Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles. |
Clonality: |
Monoclonal |
Isotype: |
IgG1 |
Concentration: |
1mg/mL |
Observed Band: |
47(51)kDa |
GeneID: |
842 |
Human Swiss-Prot No: |
P55211 |
Cellular localization: |
Cytosol,Mitochondrion,Nucleus |
Background: |
Caspase-9 is an initiator caspase, encoded by the CASP9 gene.Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). |