Product name: |
Calnexin Rabbit pAb |
Reactivity: |
Human, Rat, Mouse |
Alternative Names: |
CANX antibody, CNX antibody, FLJ26570 antibody, IP90 antibody, P90 antibody |
Source: |
Rabbit |
Dilutions: |
WB 1:1,000-2,000?? IHC 1:200-500 |
Immunogen: |
Recombinant Protein |
Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles. |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1mg/mL |
Observed Band: |
75,80,90kDa |
GeneID: |
821 |
Human Swiss-Prot No: |
P27824 |
Cellular localization: |
Endoplasmic reticulum membrane,Melanosome. |
Background: |
Calnexin is a chaperone, characterized by assisting protein folding and quality control, ensuring that only properly folded and assembled proteins proceed further along the secretory pathway. Calnexin is a integral protein (that appears variously as a 90kDa, 80kDa or 75kDa band on western blotting depending on the source of the antibody) of the endoplasmic reticulum (ER). It consists of a large (50 kDa) N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail. |