Product name: |
MEK2 Rabbit pAb |
Reactivity: |
Human, Rat, Mouse |
Alternative Names: |
ERK activator kinase 2 antibody, MAPK kinase kinase 2 antibody, MEKK2 antibody, MKK2 antibody, PRKMK 2 antibody |
Source: |
Rabbit |
Dilutions: |
WB 1:1,000-2,000?? IHC? 1:200-500 |
Immunogen: |
Recombinant Protein |
Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles. |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1mg/mL |
Observed Band: |
45kDa |
GeneID: |
5605 |
Human Swiss-Prot No: |
P36507 |
Cellular localization: |
Cytoplasm,?Membrane |
Background: |
MEK1 and MEK2, also called MAPK or Erk kinases, are dual-specificity protein kinases that function in a mitogen activated protein kinase cascade controlling cell growth and differentiation. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases. |