Product name: |
P21 Rabbit pAb |
Reactivity: |
Human, Rat, Mouse |
Alternative Names: |
CDKN1 antibody, CDKI antibody, CDKN1A antibody, MDA 6 antibody, p21 cip1 antibody, p21waf antibody |
Source: |
Rabbit |
Dilutions: |
WB 1:1,000-2,000?? IHC? 1:100-200 |
Immunogen: |
Recombinant Protein |
Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles. |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1mg/mL |
Observed Band: |
21kDa |
GeneID: |
1026 |
Human Swiss-Prot No: |
P38936 |
Cellular localization: |
Cytoplasm, Nucleus |
Background: |
p21 / WAF1 / CIP1 also known as cyclin-dependent kinase inhibitor 1 or CDK-interacting protein 1 is a protein that in humans is encoded by the CDKN1A gene. p21 is a potent cyclin-dependent kinase inhibitor (CKI). The p21 (CIP1/WAF1) protein binds to and inhibits the activity of cyclin-CDK2, -CDK1, and -CDK4/6 complexes, and thus functions as a regulator of cell cycle progression at G1 and S phase. |