Product name: |
TNF α Rabbit pAb |
Reactivity: |
Human, Rat, Mouse |
Alternative Names: |
APC1 antibody, DIF antibody, TNFSF2 antibody, Tumor necrosis factor alpha antibody |
Source: |
Rabbit |
Dilutions: |
WB 1:1,000-2,000? IHC 1:100-200 |
Immunogen: |
Recombinant Protein |
Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles. |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1mg/mL |
Observed Band: |
17,25kDa |
GeneID: |
7124 |
Human Swiss-Prot No: |
P01375 |
Cellular localization: |
Secreted,Cell membrane |
Background: |
TNF-α, the prototypical member of the TNF protein superfamily, is a homotrimeric type-II membrane protein. It can cause cytolysis of certain tumor cell lines; it is involved in the induction of cachexia; it is a potent pyrogen, causing fever by direct action or by stimulation of ?interlerukin-1 secretion; it can stimulate cell proliferation and induce cell differentiation under certain conditions.. |