Product name: |
EAAT2 Rabbit pAb |
Reactivity: |
Human, Rat, Mouse |
Alternative Names: |
Excitatory amino acid transporter 2, Slcla2, GLT1 |
Source: |
Rabbit |
Dilutions: |
WB 1:1,000-2,000 |
Immunogen: |
Synthetic Peptide |
Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles. |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1mg/mL |
Observed Band: |
62kDa |
GeneID: |
6506 |
Human Swiss-Prot No: |
P43004 |
Cellular localization: |
Membrane |
Background: |
Excitatory amino acid transporters (EAATs) regulate and maintain extracellular glutamate concentrations below excitotoxic levels. In addition, glutamate transporters may limit the duration of synaptic excitation by an electrogenic process in which the transmitter is cotransported with three sodium ions and one proton, followed by countertransport of a potassium ion. |