Product name: |
Caspase-3 (4B8) Mouse mAb |
Reactivity: |
Human, Rat, Mouse |
Alternative Names: |
APOPAIN antibody, CASP 3 antibody, CPP32 antibody, Cysterine protease CPP32 antibody |
Source: |
Mouse |
Dilutions: |
IHC 1:100-200 |
Immunogen: |
Synthetic Peptide |
Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles. |
Clonality: |
Monoclonal |
Isotype: |
IgG1 |
Concentration: |
1mg/mL |
Observed Band: |
17,32kDa |
GeneID: |
836 |
Human Swiss-Prot No: |
P42574 |
Cellular localization: |
Cytoplasm |
Background: |
Caspase-3 (CPP-32, Apoptain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins such as the nuclear enzyme poly(ADP-ribose) polymerase (PARP). |