Product name: |
Bax (6F11) Mouse mAb |
Reactivity: |
Human, Rat, Mouse |
Alternative Names: |
Apoptosis regulator bax, BAXA, BCL2 associated X protein |
Source: |
Mouse |
Dilutions: |
WB 1:1,000-2,000??? IHC 1:100-200 |
Immunogen: |
Synthetic Peptide |
Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles. |
Clonality: |
Monoclonal |
Isotype: |
IgG1 |
Concentration: |
1mg/mL |
Observed Band: |
20kDa |
GeneID: |
581 |
Human Swiss-Prot No: |
Q07812 |
Cellular localization: |
Cytoplasm,?Membrane,?Mitochondrion |
Background: |
Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. |